3/24/2023 0 Comments Rstudio confidence interval![]() Treatment costs for older men with early and late prostate cancer are already high and projected to rise in the following decades. Furthermore, the median age of men who develop the metastatic disease is considerably older, and the median age of those who die due to prostate cancer is eighty years. While the overall mortality rate is predicted to remain steady, the number of men aged 70 and older who die from prostate cancer will nearly double by 2040. Nearly 70% of PC deaths occur in men aged ≥ 75. ![]() However, at the time of diagnosis, 60% of patients are 65 years or older, and by 2040, this percentage will rise to 70%. The average age at which prostate cancer (PC) is diagnosed in western populations is 66 years old. Age-standardized incidence and mortality are 68 and 10 per 100,000, respectively, in more developed regions. Prostate cancer is the fourth most common cancer worldwide. Conclusions: Baseline G8 screening is recommended for mCRPC patients aged ≥70 to optimise ARPIs in vulnerable individuals, including early introduction of palliative care. and setting of treatment (i.e., post-ABI/ENZ) for rPFS only ( p < 0.001 and p = 0.01, respectively) age ≥78 years for OS only ( p = 0.008). At the MVA, independent prognostic factors for both worse rPFS and OS were Geriatric G8 assessment ≤ 14 ( p < 0.001 and p = 0.004) and PSA decline ≥50% ( p < 0.001 for both) time to castration resistance ≥ 31 mo. With a median follow-up of 15.4 months (mo.), the median rPFS was 26.0 mo. Results: Overall, 234 patients were enrolled with a median age of 78 years (73–82) 86 were treated with abiraterone (ABI) and 148 with enzalutamide (ENZ). ![]() Unsupervised median values and literature-based thresholds where available were used as cut-offs for quantitative variables. Cox regression univariable and multivariable analyses for radiographic progression-free (rPFS) and overall survival (OS) were performed. ![]() Methods and Materials: The Meet-URO network ADHERE was a prospective multicentre observational cohort study evaluating and monitoring adherence to ARPIs metastatic castrate-resistant PC (mCRPC) patients aged ≥70. However, prognostic factors relevant to their outcome with ARPIs are still little investigated. Introduction: Androgen receptor pathway inhibitors (ARPIs) have been increasingly offered to older patients with prostate cancer (PC). ![]()
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3/24/2023 0 Comments Thumbs up clip art![]() What are your favorite Whiteboard.fi features and why? Leave occasional blank pages to cope with unplanned asides.Don't try to write too much on each screen.Label the names of your whiteboards using a future-proof and clearly thought-through system that enables you to find them easily.What would you recommend to other teachers who are only starting to use Whiteboard.fi? I used the saved evidence from this to help for judgements about levels of progress. The speed at which this was happening meant that they didn't have time to communicate out of my sight about the 'right' answer and so I felt that I got a more genuine snapshot of what they could individually do. Whilst they didn't have a graphics tablet to write with like I did, their mouse could draw lines to link items together. Using the 'push' function to engage students during remote learning was fantastic. What do your students love most about Whiteboard.fi? The variable writing width and eraser options are in my opinion the best that I have found. In summer 2020 I tried using several other types of other software, but Whiteboard provides the smoothest writing surface with no glitches. In a classroom before covid, I would have written on the static whiteboard in the classroom which then would be lost afterward. I would feel completely wrong-footed and underprepared to cope with the various scenarios thrown our way each day1īefore Whiteboard.fi, which solutions did you use for those scenarios, and what was challenging? How would you feel if you could no longer use Whiteboard.fi? Why? Students commented after remote learning 'your lessons have been the most like normal lessons'. For example, have your students’ grades improved? List some improvements you have recorded. I would be delighted to see folders within folders in the future. It was a great step forward when 'folders' were introduced so that I could store the different whiteboards for different classes. What overall improvements have you seen with Whiteboard.fi? Students appreciate being able to 'go back a page' - once a static whiteboard is wiped, there's no going back. I am never without a board pen (as long as I have my graphics tablet!). When I write on Whiteboard.fi my handwriting looks like it does on a real whiteboard. ![]() What is the best thing about using Whiteboard.fi in a classroom setting? Using Whiteboard.fi is now my normal way of working, having written on a whiteboard in the classroom for 25 years." Having been working in-school for many months, where at 5 minutes notice the lesson may need to be live-streamed for students who had been set home, I wanted to have a set-up which I would be using in the classroom day to day as normal and then the addition of joining the lesson remotely would pose no additional burden for the students or for me. Used in conjunction with a platform for sharing the skeleton and annotated whiteboards before and after a lesson, for all students, makes reviewing ideas afterward, including for students who missed a lesson, really easy. This makes the lesson feel very familiar when I annotate them during the discussion of the lesson. For students with special needs, the slides can then be easily pdf-ed and sent in advance. What are your main scenarios and objectives for using Whiteboard.fi?īefore a lesson, I can prepare the skeleton of what the hour-long lesson will look like. How did you originally discover Whiteboard.fi?ĭuring the first few months of this academic year, I tried, along with other colleagues, many different platforms and this is the one that I chose and I am delighted to have made that choice. I wanted to use a platform that made the lessons feel as similar as possible to in-school learning from the students' point of view and as reassuring as possible from my point of view to mitigating all the other technological uncertainties that teachers were managing lesson, by lesson. I have used Whiteboard.fi over the last few months to help manage teaching classes of 30 students whilst being based as the teacher, at home. What is the biggest challenge you face in your role? Year 9-13 in the UK, so students aged 14 to 18 years old. ![]() ![]() Of course, that's all "could this, could that" - I imagine most of that isn't done. and remount the drive and restore it's state before allowing any programs to resume. ![]() Since the OS has control of which programs can run when, logically it should be able to suspend all programs, flush the caches, unmount the drive. I assume there's a raft of things happen when the OS goes to sleep, I'd expect it to flush any cashes, notify all running programs, and so on. > be there start running again? Otherwise strange unexpected consequences may happen. > Depends on timings, really - will the remount happen before an programs which *might* expect that drive to If having that network connection removed/changed causes data loss, then that **IS** the fault of OS X (or rather the people that built it). If you are a portable device, and put into sleep mode, then it's unrealistic not to anticipate there being a high likelyhood of having the network removed/changed before you wake again. You might not be able to blame OS X for the network being unplugged, but you can blame it for not handling a reasonably forseeable event. > In any case, my issue was premature removal of network connection, which you can hardly blame OS X for (or any OS for that matter). Even if you don't unmount it, the system should be able to cope with a drive being physically disconnected and reconnected again while it's asleep. ![]() IMO it's obvious that when sleeping, you should unmount any drive (or at least any drive flagged as removable) which doesn't have open files on it. yes to flushing caches, however, it may not be entirely obvious which ones to try to un-mount - some drives you wouldn't want unmounting. ![]() 3/24/2023 0 Comments Microsoft excel 2013 free download![]() If you want to install 32-bit Office instead, please run the 32-bit setup.Īfter you register for the Office 2013 Preview, you can try Microsoft Office 2013 download for 64-bit setup files which will especially make Excel users happy with its increased memory capabilities based on the 64-bit operating system it will be running on.Īfter you decide MS Office 2013 edition you want to download, you can choose among available Office 2013 languages (English, Spanish and Japanese) ![]() ![]() Please uninstall all 32-bit Office programs, then re-try installing 64-bit Office. Microsoft Office Project Professional 2010 We can't install the 64-bit version of Office because we found the following 32-bit programs on your PC: Or you can uninstall previously installed 32 bit applications, and then install 圆4 Microsoft Office 2013 Professional Plus preview (beta) version. So if you have already installed Office products of 32 bit, then you can try free Microsoft Office 2013 download of 32-bit distribution binaries and install 32 bit Office applications. One important note to choose x86 or 圆4 versions of Microsoft Office 2013 for Office users is previously installed Office products require the same product architecture family for new Office 2013 Preview applications too. ![]() This Microsoft TechNet page will not only provide you required activation keys (Office 2013 product key) but also links to 32 bit and 64 bit binaries of Microsoft Office 2013 Professional Plus setup files. Then you will be redirected to TechNet Product Key Distribution for Office 2013 pages. If you follow this download link, it will request you to login with your Passport account. ![]() 3/24/2023 0 Comments Untar tar gz file![]() ![]() Specifying mode is the best way to ensure filesystem objects are created with the correct permissions. tar file is a collection of files compressed into a single file or archive. If mode is not specified and the destination filesystem object does exist, the mode of the existing filesystem object will be used. If mode is not specified and the destination filesystem object does not exist, the default umask on the system will be used when setting the mode for the newly created filesystem object. Giving Ansible a number without following one of these rules will end up with a decimal number which will have unexpected results.Īs of Ansible 1.8, the mode may be specified as a symbolic mode (for example, u+rwx or u=rw,g=r,o=r). Create a tar file of all the program files in the current folder. Since the Tar GZ file format is native to Linux, you can use the Linux command line to execute various commands on your Tar GZ files. Untar an input file into an output file. Please note that the tar archive may contain folders as well, case in which they need to be created on the local filesystem. So, for a file tar.gz, you need to first unzip it and after that untar it.You must either add a leading zero so that Ansibleâs YAML parser knows it is an octal number (like 0644 or 01777) or quote it (like '644' or '1777') so Ansible receives a string and can do its own conversion from string into number. Create a tar file, and then extract it to the folder backup. Here are two methods: one that unzips a file and another one that untars it. The permissions the resulting filesystem object should have.įor those used to /usr/bin/chmod remember that modes are actually octal numbers. Controlling how Ansible behaves: precedence rules Run the below command in the terminal to see the contents of a tar.gz file without extracting it: tar -tf.The program, tar, will uncompress both types and extract the files from archive. (On Unix-alikes these are set at installation if found. Generally that are compressed using gzip or bzip2. Environment variable RGZIPCMD gives the command to decompress gzip files, and RBZIPCMD for bzip2 files. ![]() You may find it easier to cd /path/tar first, then you can drop the -C /path/tar from the untar command, and the /path/tar/ in the loop. Tar file can come compressed or uncompressed.
3/24/2023 0 Comments Kindergarten 2 online![]() In particular, we seem to have a lot of adults writing to us about their love for: *Brain Games* - take breaks but have fun with a brain boost!Īll sections - we have many adult users who love learning. *Create Zone*(paint, make, and create activities) *Animals* (hundreds of articles and quizzes) *Science*(Life Cycle, Plant and animal cell, deep sea creatures, movies, games) Games *(many levels and topics, many kinds of games) *Geography*(Many levels of difficulty to choose from upon skill level). *Cell Games* Learn about animal, plant and bacteria cells. *Create Zone* (paint, make, and create activities) *Health* (Games about the systems, digestion, skeleton) *Animals* (hundreds of articles and fun animal games) *Science* (Life Cycle, Plant and animal cell, movies, games) *Government Games* (balance of power, branches of govt, executive branch) *Geography* (8 skill levels - states, capitals, countries). *Grammar Games *(games, tutorial, verbs, adjectives, nouns, punctuation) *Seasons for Kids * (painting activities, matching games, winter, fall, spring, summer) Games * (many levels and topics, many kinds of games) *Preschool Animals* (movies and create activities) *Animal Kid's Corner* (upper row for older kids, lower row for younger.) *Paint Dogs* (paint 12 dogs and learn different types) *Paint Cats* (paint 7 cats and learn different types) *Earth Tips* (movies and infographics on the environment) *Seasons Paint and Make* (paint seasonal scenes and add nature and objects!) *Animal Environments Paint and Make* (paint 7 scenes and add animals!) *Easy Spanish* (colors, objects, animals) ![]() *Early Math* (counting, simple adding and subtracting, more) *Geography* (learning and lower levels - states, countries, more). *Animal Kid's Corner* (lower row - puzzles, matching games, painting) *Preschool Animals* (movies, create games, games, flashcards) *Preschool/Kindergarten* (numbers, colors, shapes, alphabet, animals) ![]() 3/24/2023 0 Comments Decode hex![]() ![]() However, they can be used in a defensive capacity. They are affiliated with Dark Magic, darker than a jinx but not as dark as a curse, and generally causes moderate suffering to the victim. What are hexes in Harry Potter?Ī hex is one of the seven known spell types. Definition of hex (Entry 2 of 5) 1 : a person who practices witchcraft. What does it mean to hex someone?Ģ : to affect as if by an evil spell : jinx. If red, green, and blue are all at the minimum 0 (represented as “00” in the code), the color expressed is the color black. The values are a special code that represents color values from 0 to 255. Hex color codes are values that tell the display how much of a color to show. Remember to convert alphabetic hex values (A, B, C, D, E, and F) to their decimal equivalent (10, 11, 12, 13, 14, and 15). Therefore 64 characters are chosen that are both members of a subset common to most encodings (ASCII), and also printable. Base64 encoding schemes are used when binary data needs to be stored or transferred as textual data. In other words, leave it be, but keep that value off to the side. Base64 to hex: Encode and decode bytes online. Multiply it by 160, that is: multiply by 1. Subscribe to the project news and updates. This is because two digits of hexadecimal can represent a whole byte, eight digits in binary. How do you solve hexadecimal codes Start with the right-most digit of your hex value. Traccar is a free and open source modern GPS tracking system. It is commonly used for programming microcontrollers, EPROMs, and other types of programmable logic devices and hardware emulators.ALSO READ how to decode hexadecimal code in java Do computers use binary or hexadecimal?Īlthough computers don’t run on hexadecimal, programmers use it to represent binary addresses in a human-readable format when writing code. Intel hexadecimal object file format, Intel hex format or Intellec Hex is a file format that conveys binary information in ASCII text form. The space character, that denotes the space between words, as produced by the space-bar of a keyboard, represented by code 0x20 (hexadecimal), is considered a non-printing graphic (or an invisible graphic) rather than a control character. Likewise you can generate the ASCII code from the number by adding 30h or by ORing with 30h. If you have the ASCII code for a number you can either subtract 30h or mask off the upper four bits and you will be left with the number itself. Each 6 bits of the bit stream are encoded to base64 digit. The color values are defined in values between 00 and FF (instead of from 0 to 255 in RGB). The text input is first encoded as binary bit stream of ASCII codes of each character. So the hex-representation of this is 04 and 2B (or vice versa depending on the byte order). About, Data Protection & Imprint The information on the modrewrite cheat sheet is without any commitment. Let's start with the first character: this is 1067 in the Unicode table. Hex is utilized since it is shorter and takes up less memory for this reason. The first two letters/numbers refer to red, the next two refer to green, and the last two refer to blue. Give our bin2hex encode/decode tool a try bin2hex encode or bin2hex decode any string with just one mouse click. Hex color codes start with a pound sign or hashtag (#) and are followed by six letters and/or numbers. Decode Hex String in Python 3 Ask Question 79 In Python 2, converting the hexadecimal form of a string into the corresponding unicode was straightforward: code ('hex') where the variable 'comments' is a part of a line in a file (the rest of the line does not need to be converted, as it is represented only in ASCII. ALSO READ how to decode hex numbers How do you read a color code? ![]() 3/23/2023 0 Comments Essential video tools suite![]() ![]() The paid version of this tool supports 4K videos, but the free version does not. The tool supports a wide variety of video formats and has a lot of video and audio editing options. Some of its best features include high precision video trimming, multi-cam support, and the ability to export to 720p for YouTube. However, the free version is more than enough for non-professional use. This is another powerful video editing software solution power-packed with useful features. ![]() □ Simple to use tool for day-to-day video editing.You can get more advanced features with VSDC Pro for $19.99. While the Pro version gives you access to even more tools, the free version is by no means lacking. VSDC is a full-featured video editing tool with visual and audio effects, blending modes, filters, and more. Despite the simplicity of the interface, the program offers plenty of features that allow users to create long and complex videos. VSDC has a modern and intuitive interface that makes use of different wizards so video creation and editing are simple and hassle-free. Blending modes and Instagram-like filters.It’s relatively simple to use and has features like color correction, visual and audio effects, blending modes and filters, etc. For professionals, the paid version offers more advanced features. The free version is good enough for almost all of your routine video editing needs. It’s a good video editing software solution that supports almost all video formats and codecs. This is an open-source, free video editor available only on Windows. □ It lags sometimes, which is inconvenient.Plus, the developers are super engaged in their work on the platform so new features are always rolling out. There’s also a great selection of effects like transitions, transforms, titles, and animations easily accessible from the Effects tab. OpenShot offers tons of features from basic to advanced editing. Setting up your assets on the timeline is also really easy and you can also trim the music and videos by simply dragging the right slider to the time you want. You can import your own videos, photos, or music via drag-and-drop or right-clicking on the Project Files tab and choosing Import. OpenShot is easy to use and has an intuitive user interface. Drag and drop video, audio, or images right into the editor.Add as many layers as you need for watermarks, background videos, audio tracks, and more.Cross-platform video editor, with support for Linux, Mac, and Windows. ![]() Moreover, it is extremely easy to cut and slice any video using this tool. It provides advanced features like unlimited layers, video transitions with real-time previews, and has lots of options for video effects, animation, and keyframes. It’s a powerful video editor packed with numerous useful features and has a simple-to-use, drag-and-drop interface that even beginners can use easily. OpenShot is one of the best open-source free video editing software solutions in the market. From there, we'll share 38 additional free video editing software tools that you can use to create awesome, visually appealing messages for your business. We're going to start things off by taking a look at two different types of video editing software: standard video editing software and promo video editing software. Some of these platforms also work on multiple devices and operating systems, providing truly omnichannel video-editing convenience.īest Free Video Editing Software for 2023: We'll include a mix of software for desktop as well as mobile apps you can use to edit and share your videos. And, no, this isn't just a long list of video editing software, it's a hand-curated list of the best free video editors that are both easy-to-use and provide value. In this guide, we'll take a deep dive into the best free video editing software solutions available today. It’s always more fun to enhance it and add cool effects, sounds, and filters, right? If you can relate to this, then you've come to the right place. Most of us don't have the magical skill to create the perfect video in one go. If you're anything like us, you've shot a video for social media that you've wanted to make more interesting. Our partners cannot pay us to guarantee favorable reviews of their products or services. Our reviews are based on years of experience and countless hours of research. This may influence which products or services we review (also where and how those products appear on the site), this in no way affects our recommendations or the advice we offer. ![]() 3/23/2023 0 Comments Radio silence quotes![]() ![]() The more powerful the magic, the more likely it is to be noticed using the Elfstones is like setting off a flare. In the Shannara series, any use of magic tends to reveal the user's location to his or her enemies.Note that this requires far more than simply not making radio transmissions-much of their technology relies on wireless communications, even between different components of the same item. The Roanoke colonists are forced to do this in The Last Colony by foregoing the use of their technology. ![]()
3/23/2023 0 Comments Cuisine royale age of nagual pack![]() ![]() So if you see a butterfly or a drone - you should know that you are being watched. In order to mitigate any advantage of the latter, every player has a familiar with a camera that can uncover the position of a player who is peeking around a corner. Fair play TPV: you can play in first or third person view.There are regular special events in the game with new rules and setups of battles and a system of daily tasks and secret missions rewarding players with unique items and powers.Stand out from the crowd with different costumes, masks, talismans, hats, gestures, graffiti and even underwear! Unlock new spirit-guardians to get additional tactical abilities in the battles.But first, one needs to collect sinner souls for killing enemies - to be able to pay for most of that luxury. You can flood the whole map or cause the sun to eclipse, set up traps, summon zombies or teleport yourself or others the hell out of here. There are mystical powers in game! Draw seals with your blood or conduct ancient rituals, throw hex bags at enemies and use your own special power.Different vehicles, military amphibians and speed boats will help to cover distances. There are few compromises in the game regarding physics or ballistics rules. A constantly growing collection of realistically modelled weapons and armor, including anti-materiel guns, sniper rifles, assault rifles, rocket launchers, flamethrowers and mortars.Different champions to select - each one with a unique superpower.All the while, the battlefield itself shrinks constantly, surrounded by the deadly Dark Zone. Massive and dense PvP battles: dozens of players begin their trip in one of the four picturesque and detailed locations, fighting their way to the centre of the battlefield.– is a brutal MMO last-man-standing shooter with realistic weaponry, elements of lethal mystic forces and incredible superpowers! If the above steps do not help, you can contact the webmaster via email: and refer to incident number #59833.CRSED: F.O.A.D. Once your system is cleaned of viruses and spyware, please try your request again.Īs a first measure, Microsoft Security Essentials can be a useful free addition if you do not have such tools installed or available, but it is no by means complete. Ensure that you have REAL anti-virus and anti-spyware software on your computer, that they are kept up-to-date, and that you have run a full system scan using each tool. This problem can be caused by viruses or spyware on your computer, or by malicious software that pretends to be anti-virus or anti-spyware software. Oppdateringer, begivenheter og nyheter fra utviklerne av Cuisine Royale - Age of Nagual Pack. (Example: If you use Norton Internet Security, it has a Stealth Mode Browsing feature that interferes with proper Internet operation.) Weird West: Age of Nagual / Cuisine Royale Watch on Gaijin Entertainment and Darkflow Software are thrilled to announce the release of a major Content Update for CUISINE ROYALE, a brutal multiplayer shooter available free-to-play on PC and Xbox One. If you are using something like this, you need to either turn it off or change its settings before trying again. This problem can be happen when there is browser privacy software or personal firewall software that was not set-up properly, or has bugs in it. If this is not an option, please contact the server administrator. Normally you will need to uninstall the software, since invariably just disabling it is not enough. This problem is often associated with proxy servers and systems that are not set up properly. Your browser sent a request for the page that was not valid. The information for this was supplied by Bad Behavior. ![]() ![]() Fortunately the problem is normally quite easy to fix. We apologize for the inconvenience, but we are unable to complete your request as part of protection against spreading bad things like spam and malware, the defenses of this site found potentially suspicious behavior that matched that of known spammers and/or malware distributors. ![]() |
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